The immunopathogenesis of cryptococcal immune reconstitution inflammatory syndrome
نویسندگان
چکیده
منابع مشابه
Cryptococcal immune reconstitution inflammatory syndrome following alemtuzumab therapy.
Alemtuzumab is a lymphocyte ablative agent that may cause susceptibility to severe opportunistic infections similar to those seen in AIDS. Pathogen-specific immune reconstitution syndromes can complicate antiretroviral therapy and immune recovery in HIV-infected patients. We present the first reported case of immune reconstitution syndrome associated with T lymphocyte recovery after alemtuzumab...
متن کاملImmune Reconstitution Inflammatory Syndrome in Acquired Immune Deficiency Syndrome related to Cryptococcal Meningoencephalitis
Background. Highly active antiretroviral therapy (HAART) has contributed to reducing the occurrence of opportunistic infections and mortality in human immunodeficiency virus (HIV) infected patients. However, a paradoxical worsening of clinical signs and symptoms among patients during HAART may occur. Immune reconstitution inflammatory syndrome (IRIS) is described as a paradoxical deterioration ...
متن کاملImmune reconstitution inflammatory syndrome.
Immune reconstitution inflammatory syndrome (IRIS) is a collection of inflammatory disorders associated with paradoxical worsening of preexisting infectious processes after the initiation of highly active antiretroviral therapy (HAART) in human immunodeficiency virus (HIV)-infected individuals. At the initial stage of the disease, the imaging findings can be misdiagnosed as pneumonia resulting ...
متن کاملCellular Immune Activation in Cerebrospinal Fluid From Ugandans With Cryptococcal Meningitis and Immune Reconstitution Inflammatory Syndrome
BACKGROUND Human immunodeficiency virus (HIV)-associated cryptococcal meningitis (CM) is characterized by high fungal burden and limited leukocyte trafficking to cerebrospinal fluid (CSF). The immunopathogenesis of CM immune reconstitution inflammatory syndrome (IRIS) after initiation of antiretroviral therapy at the site of infection is poorly understood. METHODS We characterized the lineage...
متن کاملCytomegalovirus immune reconstitution inflammatory syndrome
28 Background: Appendicitis occurs with increased frequency in HIV infected compared to 29 HIV uninfected persons. CMV-related appendicitis specifically presents with typical 30 appendicitis symptoms including surgical abdomen, fever and leukocytosis and may have 31 a more severe course with higher mortality than other types of infective appendicitis. We 32 report the first case of CMV appendic...
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ژورنال
عنوان ژورنال: Current Opinion in Infectious Diseases
سال: 2016
ISSN: 0951-7375
DOI: 10.1097/qco.0000000000000224